Thyroid Problems? Listen to your cells!

As the ever-increasing numbers of people diagnosed with the various forms of thyroid gland dysfunction will tell you, correcting the problem is more than just swallowing your prescribed Thyroxin medication*.

The incredible interactive complexity of hormones, nutrients and synthesis-conversion processes to ultimately enable thyroid receptor expression** by active Triiodothyronine (T3) thyroid hormone is one of the marvels of our physiology, and medical researchers spend a happy lifetime studying it!

It’s beyond the scope and intention of this article to detail the many intricate processes of thyroid function; here instead is the concerned or interested reader’s overview:

Nutrients: minerals, trace elements and vitamins are all required in synergistic balance to synthesise (produce) thyroid hormone, as well as drive it. Of these the ones generally regarded as most important are Iron, Vitamin D, Iodine, Zinc and Selenium.

For the thyroid-adrenal axis to be optimal, the above nutrients should be at ideal ‘target’ levels, and the respective receptors should be in balance: –T3 (active thyroid hormone), Vitamin D (D3), Cortisol (CC) receptors – of these T3 is most important (Van Zanden: 2012).

T3, D3 and Cortisol exert their actions by binding to receptors on genes in the cell nucleus; D3 has a qualitative effect on T3 intra-nuclear receptors (i.e.: within the cell nucleus).

Cortisol has a quantitative effect by increasing intra-nuclear T3 receptor density, whilst there is also a constant ‘cross talk’ between D3 & T3 intra-nuclear nuclear receptors (Van Zanden: 2017).

Crystal clear now?!! I thought so….!

My enduring gratitude to Dr. Philip Van Zanden (UNSW) for his tutorial ‘gems’ over paleo luncheons!


Copyright Anthony Pearce 2017